Active Recombinant Mouse Il19 Protein (Leu25-Ala176), C-His tagged, Animal-free, Carrier-free

• Cat.No.: Il19-150M
• Product Overview: Recombinant Mouse Il19 Protein (Leu25-Ala176) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Leu25-Ala176
• Description: Interleukin 19 (IL-19) predicts a molecular mass of 35.8 kDa, is a type of anti-inflammatory cytokine. It promotes the Th2 T-cell response which supports an anti-inflammatory lymphocyte phenotype, dampens the Th1 T-cell response and IFNγ secretion, increases IL-10 expression in peripheral blood mononuclear cells, and inhibits the production of IgG from B cells.
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce proliferation in BaF3 cells transfected with human IL-20 R alpha and human IL-20 R beta. The ED50 for this effect is < 0.6 ng/mL.
• Molecular Mass: The protein has a calculated MW of 18.54 kDa.
  The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: Il19 interleukin 19 [ Mus musculus (house mouse) ]
• Official Symbol: Il19
• Synonyms: IL19; interleukin 19; interleukin-19; IL-19
• Gene ID: 329244
• mRNA Refseq: NM_001009940
• Protein Refseq: NP_001009940
• UniProt ID: Q8CJ70