DLK1
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Official Full Name
delta-like 1 homolog -
Overview
DLK1 (delta-like-1), also known as fetal antigen 1 (FA1) and preadipocyte factor 1 (pref-1), is a member of the epidermal growth factor (EGF)-like family of proteins, containing six tandem EGF-like repeats. DLK1 is a paternally expressed, imprinted gene t -
Synonyms
DLK1;delta-like 1 homolog (Drosophila);delta like homolog (Drosophila);protein delta homolog 1;Delta1;FA1;pG2;Pref 1;ZOG;DLK-1;secredeltin;fetal antigen 1;preadipocyte factor 1;DLK;PREF1;Pref-1
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Chicken
- Rat
- E.coli
- HEK293
- Mammalian cells
- Insect Cell
- Wheat Germ
- Mammalian Cell
- HEK293T
- In Vitro Cell Free System
- Yeast
- GST
- Fc
- His
- Flag
- Non
- Myc&DDK
- His&GST
- His&T7
- His&Fc&Avi
- Flag&Myc
Involved Pathway
DLK1 involved in several pathways and played different roles in them. We selected most pathways DLK1 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus,Adipogenesis,FOXA2 and FOXA3 transcription factor networks, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by NOTCH | TLE3,MDK,MDKB,DTX2,TLE2,TLE4,HEYL,MDKA,DNER,RAB6A |
| Signal Transduction | CCK,RGS6,OR56A1,OPN4,SHARPIN,FOXH1,ROR1,ABI1B,RDH10,GPBAR1 |
| Notch signaling pathway | HER6,YY1,NOTCH2,DLB,RBPJA,DTX3,CIR1,JAG1B,NUMB,NOTCH3 |
| Activated NOTCH1 Transmits Signal to the Nucleus | DTX2,JAG2,DNER,JAG1,ADAM10,CNTN1,MIB1 |
| Adipogenesis | NR2F1,KLF6,CEBPB,PIANP,KLF7A,KLF5,NAMPT,SPOCK1,AGPAT2,HMGA1-RS1 |
| FOXA2 and FOXA3 transcription factor networks | CPT1A,CPT1B,CPT1C,UCP2,KCNJ11,FOXA1,TTR,CEBPA,FOXF1 |
| Signaling by NOTCH1 | HEYL,TLE3,DNER,DTX2 |
Protein Function
DLK1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DLK1 itself. We selected most functions DLK1 had, and list some proteins which have the same functions with DLK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | NXPE4,TTC36,SPINT4,GARNL3,STRUMPELLIN,FSD1L,LRRC66,GTSE1,GM7903,DSCR3 |
Interacting Protein
DLK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLK1.
DLK1 Related Signal Pathway
Resources
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References
- Ito, K; Yanagida, A; et al. Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts. LIVER INTERNATIONAL 34:1378-1390(2014).
- Persson-Augner, D; Lee, YW; et al. Delta-Like 1 Homologue (DLK1) Protein in Neurons of the Arcuate Nucleus That Control Weight Homeostasis and Effect of Fasting on Hypothalamic DLK1 mRNA. NEUROENDOCRINOLOGY 100:209-220(2014).
