Recombinant Human DLK1 Protein, MYC/DDK-tagged

• Cat.No.: DLK1-001H
• Product Overview: Recombinant protein of human delta-like 1 homolog (Drosophila) (DLK1) with C-MYC/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 38.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: DLK1 delta like non-canonical Notch ligand 1 [ Homo sapiens (human) ]
• Official Symbol: DLK1
• Synonyms: protein delta homolog 1; delta-like 1 homolog; fetal antigen 1; preadipocyte factor 1; secredeltin; DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1
• Gene ID: 8788
• mRNA Refseq: NM_003836
• Protein Refseq: NP_003827
• MIM: 176290
• UniProt ID: P80370