Recombinant Swine Chemokine (C-X-C motif) Ligand 10

• Cat.No.: CXCL10-148S
• Product Overview: Recombinant Swine CXCL10 protein was expressed inYeastand purified by using Ion-exchange chromatography, 9.3 kDa (82 aa).

Specification

• Species: Pig
• Source: Yeast
• Tag: Non
• Description: Chemokine (C-X-C motif) ligand 10 (CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (γ-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts.
• Sequences Of Amino Acids: PLSRTVRCTC IKISDRPVNP RSLEKLEMIP ASQSCPHVEI IATMKKNGEK RCLNPESKTI KNLLKAISKE RSKRSPRTQR EA.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Purification: Ion-exchange chromatography.
• Biological Activity: The biological activity of recombinant swine CXCL10 was determined in a chemotaxis assay using a Boyden chamber. Swine PBMCs were activated with PHA for 3 days followed by treatment with IL-2. Bioactivity is typically detected at 10 ng/mL.
• Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
• Pathways: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway

Gene Information

• Gene Name: CXCL10 chemokine (C-X-C motif) ligand 10 [ Sus scrofa ]
• Synonyms: CXCL10; chemokine (C-X-C motif) ligand 10; small-inducible cytokine B10; chemokine CXC-like protein; chemokine C-X-C motif ligand 10
• Gene ID: 494019
• mRNA Refseq: NM_001008691
• Protein Refseq: NP_001008691