Recombinant Rhesus Macaque Growth Arrest And DNA-damage-inducible, Alpha

• Cat.No.: GADD45A-5195R
• Product Overview: RecombinantRhesus Macaque GADD45A is a single, non-glycosylated polypeptide chaincontaining 165 amino acids.

Specification

• Species: Rhesus macaque
• Source: Rhesus Macaque
• Tag: Non
• Description: GADD45Ais a member of the GADD45 family of proteins. It is ubiquitously expressed,and induced by DNA damage. Upon induction, GADD45A binds to PCNA, stimulatesDNA excision repair, and initiates G2 cell cycle arrest.
• Form: Lyophilized from a 0.2 um sterile filteredsolution of PBS, pH 7.4.
• Purity: >95%by SDS-PAGE and HPLC analyses.
• Sequence: MTLEEFSAGEQKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQAFCCENDINIL RVSNPGRLAE LLLLETDAGP AATEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVINLPER
• Molecular Weight: 18.3 kDa
• Endotoxin: <0.1 ng/μg of Protein
• Reconstitution: Centrifugevial prior to opening. Add sterile distilled water or aqueousbuffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be dividedinto working aliquots and stored at -80°C. Further dilutions should bemade in appropriate buffered solutions.
• Storage: The lyophilized protein is stable at2-4°C, but should be kept desiccated at -20°C for long term storage. Afterreconstitution, the protein is stable for 1 week at 2-4°C. For long termstorage, aliquot and freeze at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: GADD45A
• Pathways: Cell cycle; MAPKsignaling pathway; p53 signaling pathway

Gene Information

• Gene Name: GADD45A growth arrest andDNA-damage-inducible, alpha [ Macaca mulatta ]
• Synonyms: GADD45A; growtharrest and DNA-damage-inducible, alpha; ENSMMUP00000019436; ENSMMUP00000039965
• Gene ID: 701054
• mRNA Refseq: XM_001095413
• Protein Refseq: XP_001095413
• UniProt ID: F6W540
• Chromosome Location: 1