Recombinant Mouse Gadd45a Protein, Myc/DDK-tagged

• Cat.No.: Gadd45a-3130M
• Product Overview: Purified recombinant protein of mouse full-length growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 18.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gadd45a growth arrest and DNA-damage-inducible 45 alpha [ Mus musculus (house mouse) ]
• Official Symbol: Gadd45a
• Synonyms: GADD45A; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA damage-inducible protein GADD45 alpha; DDIT-1; Gadd45alpha; DNA-damage inducible transcript 1; DNA-damage-inducible transcript 1; DNA damage-inducible transcript 1 protein; growth arrest and DNA-damage-inducible, alpha; growth arrest and DNA-damage-inducible protein GADD45 alpha; Ddit1; GADD45; AA545191
• Gene ID: 13197
• mRNA Refseq: NM_007836
• Protein Refseq: NP_031862
• UniProt ID: P48316