Recombinant Rat Tg Protein, His-tagged

• Cat.No.: Tg-2125R
• Product Overview: Recombinant Rat Tg Protein (Cys1150-Cys1509) with N-His tag was expressed in E. coli.

Specification

• Description: Enables several functions, including anion binding activity; chaperone binding activity; and identical protein binding activity. Involved in several processes, including response to lipopolysaccharide; thyroid hormone generation; and transcytosis. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and perinuclear region of cytoplasm. Part of protein-containing complex. Used to study hypothyroidism and isolated growth hormone deficiency. Human ortholog(s) of this gene implicated in Graves' disease; autoimmune thyroiditis; goiter; and thyroid dyshormonogenesis 3. Orthologous to human TG (thyroglobulin).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.3 kDa
  Accurate Molecular Mass: 43 kDa
• Protein length: Cys1150-Cys1509
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Tg thyroglobulin [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Tg
• Synonyms: TG; thyroglobulin; Tgn
• Gene ID: 24826
• mRNA Refseq: NM_030988
• Protein Refseq: NP_112250
• UniProt ID: P06882