Recombinant Rat Phosphodiesterase 10A, GST-tagged

• Cat.No.: Pde10a-439R
• Product Overview: Recombinant rat Pde10a, amino acids 449-end with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 66kDa.

Specification

• Cat. No.: Pde10a-439R
• Description: Phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene.
• Source: Sf9 cell.
• Purity: >80%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.
• Protein length: 449-end a.a.

Gene Information

• Gene Name: Pde10a phosphodiesterase 10A [ Rattus norvegicus ]
• Synonyms: Pde10a; phosphodiesterase 10A; Pde10a3; testis-specific phosphodiesterase PDE10A2
• Gene ID: 63885
• mRNA Refseq: NM_022236
• Protein Refseq: NP_071572
• UniProt ID: Q9QYJ6
• Chromosome Location: 1q11
• Pathway: Progesterone-mediated oocyte maturation; Purine metabolism
• Function: 3",5"-cyclic-GMP phosphodiesterase activity; 3",5"-cyclic-nucleotide phosphodiesterase activity; cGMP binding; cAMP binding; cyclic-nucleotide phosphodiesterase activity; drug binding