Recombinant Rat Per2 protein, His & T7-tagged

• Cat.No.: Per2-1924R
• Product Overview: Recombinant Rat Per2 aa. (Ile179~Pro436 (Accession # Q9Z301)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Rat
• Source: E.coli
• Tag: His&T7
• Protein Length: Ile179~Pro436
• Description: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.2kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.7

Gene Information

• Gene Name: Per2 period circadian clock 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Per2
• Synonyms: Per2; period circadian clock 2; rPER2; period circadian protein homolog 2; circadian clock protein PERIOD 2
• Gene ID: 63840
• mRNA Refseq: NM_031678.1
• Protein Refseq: NP_113866.1
• UniProt ID: Q9Z301