Recombinant Rat Pclo Protein, His-tagged

• Cat.No.: Pclo-1926R
• Product Overview: Recombinant Rat Pclo Protein (Leu4871-His5085) with N-His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Protein Length: Leu4871-His5085
• Description: Enables calcium ion binding activity; calcium-dependent phospholipid binding activity; and transcription corepressor binding activity. Involved in several processes, including positive regulation of synaptic vesicle recycling; presynaptic active zone assembly; and regulation of endosome size. Located in several cellular components, including cytoplasmic vesicle; distal axon; and rod spherule. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Orthologous to human PCLO (piccolo presynaptic cytomatrix protein).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.5 kDa
  Accurate Molecular Mass: 33 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Pclo piccolo (presynaptic cytomatrix protein) [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Pclo
• Synonyms: PCLO; piccolo (presynaptic cytomatrix protein); protein piccolo; presynaptic cytomatrix protein; multidomain presynaptic cytomatrix protein Piccolo; aczonin
• Gene ID: 56768
• mRNA Refseq: NM_001110797
• Protein Refseq: NP_001104267
• UniProt ID: Q9JKS6