Recombinant Rat Dlg1 Protein, His-tagged

• Cat.No.: Dlg1-1345R
• Product Overview: Recombinant Rat Dlg1 Protein (Ala686-Ala907) with N-His tag was expressed in E. coli.

Specification

• Description: Enables several functions, including PDZ domain binding activity; ionotropic glutamate receptor binding activity; and kinesin binding activity. Involved in several processes, including cell adhesion; neurotransmitter receptor localization to postsynaptic specialization membrane; and positive regulation of potassium ion transport. Located in several cellular components, including basolateral plasma membrane; lateral plasma membrane; and paranode region of axon. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of Parkinson's disease. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.4 kDa
  Accurate Molecular Mass: 29 kDa
• Protein length: Ala686-Ala907
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Dlg1 discs, large homolog 1 (Drosophila) [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Dlg1
• Synonyms: DLG1; discs, large homolog 1 (Drosophila); disks large homolog 1; SAP-97; synapse-associated protein 97; Drosophila discs-large tumor suppressor homologue (synapse associated protein); Dlgh1; SAP97
• Gene ID: 25252
• mRNA Refseq: NM_012788
• Protein Refseq: NP_036920
• UniProt ID: Q62696