Recombinant Rat Crp Protein, His-tagged

• Cat.No.: Crp-358R
• Product Overview: Recombinant rat CRP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Rat
• Source: Insect Cells
• Tag: His
• Description: CRP, also known as c-reactive protein, displays several functions associated with host defense. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine and can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 24.1kDa (217aa)28-40KDa (SDS-PAGE under reducing conditions.)
• AA Sequence: HEDMSKQAFV FPGVSATAYV SLEAESKKPL EAFTVCLYAH ADVSRSFSIF SYATKTSFNE ILLFWTRGQG FSIAVGGPEI LFSASEIPEVPTHICATWES ATGIVELWLD GKPRVRKSLQ KGYIVGTNAS IILGQEQDSY GGGFDANQSL VGDIGDVNMW DFVLSPEQIN AVYVGRVFSPNVLNWRALKY ETHGDVFIKP QLWPLTDCCE SHHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Crp C-reactive protein, pentraxin-related [ Rattus norvegicus ]
• Official Symbol: Crp
• Synonyms: CRP; C-reactive protein, pentraxin-related; C-reactive protein; C-reactive protein, petaxin related; C-reactive protein member of the pentraxin family; C-reactive protein, member of the pentraxin family; Aa1249; Ac1262; Ab1-341; Ab2-196; Ac1-114; Ac2-069; Ba2-693
• Gene ID: 25419
• mRNA Refseq: NM_017096
• Protein Refseq: NP_058792
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: cholesterol binding; low-density lipoprotein particle binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity