Native Human C-Reactive Protein, Pentraxin-Related

• Cat.No.: CRP-5299H
• Product Overview: Native human highpurified CRP was expressed in Human Pleural fluid.

Specification

• Species: Human
• Source: Human Pleural Fluid
• Tag: Non
• Description: CRP is a proteinfound in the blood, the levels of which rise in response to inflammation. Itsphysiological role is to bind to phosphocholine expressed on the surface ofdead or dying cells (and some types of bacteria) in order to activate thecomplement system via the C1Q complex.
• Form: Liquid, Supplied as a solution in0.05 M Tris buffer containing 0.25 M Sodium Chloride, 0.005 M CalciumChloride, and 0.1% sodium azide, pH 8.0, filter sterilized through a 0.2 μMmembrane.
• Concentration: 2.56 mg/ml
• Purity: >98% by SDS Page
• Storage: Centrifugevial prior to opening. Store at 4°C.
• Pathways: Classical antibody-mediated complementactivation; Complement cascade; Creation of C4 and C2 activators; IL6-mediatedsignaling events; Initial triggering of complement; Innate Immune System;Selenium Pathway

Gene Information

• Gene Name: CRPC-reactive protein, pentraxin-related [ Homo sapiens ]
• Official Symbol: CRP
• Synonyms: CRP; C-reactive protein,pentraxin-related; PTX1; pentraxin1; OTTHUMP00000033307; OTTHUMP00000033308;OTTHUMP00000033309; OTTHUMP00000033310; C-reactive protein; C-reactiveprotein (1-205); MGC149895; MGC88244
• Gene ID: 1401
• mRNA Refseq: NM_000567
• Protein Refseq: NP_000558
• MIM: 123260
• UniProt ID: P02741
• Chromosome Location: 1q21-q23
• Function: Gram-positivebacterial cell surface binding; binding; cholesterol binding; cholinebinding; low-density lipoprotein particle binding; metal ion binding; proteinbinding; protein homodimerization activity