Recombinant Rat C1QA Protein, His (Fc)-Avi-tagged

• Cat.No.: C1QA-699R
• Product Overview: Recombinant Rat C1QA with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rat
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: C1qa complement component 1, q subcomponent, A chain [ Rattus norvegicus ]
• Official Symbol: C1QA
• Gene ID: 298566
• mRNA Refseq: NM_001008515.1
• Protein Refseq: NP_001008515.1
• UniProt ID: P31720

Reviews

01/23/2022

Excellent quality, fast delivery.

03/01/2021

Reliable in experiments, quality.

02/09/2020

Product met all requirements.

Q&As

What role does C1QA play in the clearance of apoptotic cells?

It plays a role in recognizing and promoting the removal of apoptotic cells.

What therapeutic strategies are being explored involving C1QA modulation?

Strategies are being explored to modulate C1QA activity in conditions like lupus and rheumatoid arthritis.

Are there known genetic mutations in C1QA associated with specific health conditions?

Genetic deficiencies in C1QA are linked to increased susceptibility to infections and autoimmune conditions.

In which immune responses is C1QA critically involved?

C1QA is involved in immune responses against pathogens and in the clearance of immune complexes.

How is C1QA implicated in autoimmune diseases?

Dysregulation of C1QA can contribute to impaired clearance of immune complexes, leading to autoimmune diseases.

How does C1QA contribute to the activation of the complement system?

It binds to antibodies or C-reactive protein on pathogen surfaces, activating C1r and C1s in the C1 complex.

What is the primary function of C1QA in the immune system?

C1QA is a vital component of the C1 complex, initiating the classical complement pathway.