Recombinant Mouse Vac14 Protein, Myc/DDK-tagged

• Cat.No.: Vac14-6890M
• Product Overview: Purified recombinant protein of mouse full-length Vac14 homolog (S. cerevisiae) (Vac14), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 5-phosphate (PtdIns5P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
• Molecular Mass: 88.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vac14 Vac14 homolog (S. cerevisiae) [ Mus musculus (house mouse) ]
• Official Symbol: Vac14
• Synonyms: VAC14; Vac14 homolog (S. cerevisiae); protein VAC14 homolog; vacuole morphology 14; Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 2; Trx; ingls; Tax1bp2; AA959718; BC032215; D8Wsu151e; MGC38230
• Gene ID: 234729
• mRNA Refseq: NM_146216
• Protein Refseq: NP_666328
• UniProt ID: Q80WQ2