Recombinant Mouse Uba2 Protein, Myc/DDK-tagged

• Cat.No.: Uba2-6765M
• Product Overview: Purified recombinant protein of mouse full-length ubiquitin-like modifier activating enzyme 2 (Uba2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
• Molecular Mass: 70.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Uba2 ubiquitin-like modifier activating enzyme 2 [ Mus musculus (house mouse) ]
• Official Symbol: Uba2
• Synonyms: UBA2; ubiquitin-like modifier activating enzyme 2; SUMO-activating enzyme subunit 2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; anthracycline-associated resistance ARX; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; Arx; Sae2; UBA1; Ubl1a2; Uble1b; AA986091
• Gene ID: 50995
• mRNA Refseq: NM_016682
• Protein Refseq: NP_057891
• UniProt ID: Q9Z1F9