Recombinant Mouse Triap1 Protein, Myc/DDK-tagged

• Cat.No.: Triap1-6639M
• Product Overview: Purified recombinant protein of mouse full-length TP53 regulated inhibitor of apoptosis 1 (Triap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
• Molecular Mass: 8.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Triap1 TP53 regulated inhibitor of apoptosis 1 [ Mus musculus (house mouse) ]
• Official Symbol: Triap1
• Synonyms: Triap1; TP53 regulated inhibitor of apoptosis 1; Wf-1; P53csv; AU020874; AU043831; 1810015M01Rik; TP53-regulated inhibitor of apoptosis 1; p53-inducible cell-survival factor; protein 15E1.1
• Gene ID: 69076
• mRNA Refseq: NM_026933
• Protein Refseq: NP_081209
• UniProt ID: Q9D8Z2