Recombinant Mouse Traf6 Protein, Myc/DDK-tagged

• Cat.No.: Traf6-6621M
• Product Overview: Purified recombinant protein of mouse full-length TNF receptor-associated factor 6 (Traf6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the TNF receptor associated factor (TRAF) family of adaptor proteins that mediate signaling events from members of the TNF receptor and Toll/IL-1 receptor families to activate transcription factors such as NF-kappa-B and AP-1. The product of this gene is essential for perinatal and postnatal survival. Mice deficient in this protein exhibit osteopetrosis and defective in development of epidermal appendixes, normal B cell differentiation, lymph node organogenesis, interleukin-1 signaling, lipopolysaccharide signaling and neural tube closure. This protein possesses ubiquitin ligase activity. Alternate splicing of this gene results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 60.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Traf6 TNF receptor-associated factor 6 [ Mus musculus (house mouse) ]
• Official Symbol: Traf6
• Synonyms: TRAF6; TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; AI851288; 2310003F17Rik; C630032O20Rik
• Gene ID: 22034
• mRNA Refseq: NM_009424
• Protein Refseq: NP_033450
• UniProt ID: P70196