Recombinant Mouse Tprkb Protein, Myc/DDK-tagged

• Cat.No.: Tprkb-6610M
• Product Overview: Purified recombinant protein of mouse full-length Tp53rk binding protein (cDNA clone MGC:37089 IMAGE:4951567), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
• Molecular Mass: 19.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tprkb Tp53rk binding protein [ Mus musculus (house mouse) ]
• Official Symbol: Tprkb
• Synonyms: Tprkb; Tp53rk binding protein; DRWM; DRWMS1; Cgi-121; mDRWMS1; 0610033G21Rik; 1810034M08Rik; EKC/KEOPS complex subunit Tprkb; PRPK-binding protein; Prpk (p53-related protein kinase)-binding protein; TP53RK-binding protein
• Gene ID: 69786
• mRNA Refseq: NM_176842
• Protein Refseq: NP_789812
• UniProt ID: Q8QZZ7