Recombinant Mouse Tfr2 Protein, His-tagged

• Cat.No.: Tfr2-2123M
• Product Overview: Recombinant Mouse Tfr2 Protein (His493-Asn785) with N-His tag was expressed in E. coli.

Specification

• Description: Predicted to enable co-receptor binding activity and transferrin receptor activity. Acts upstream of or within iron ion homeostasis. Part of HFE-transferrin receptor complex. Is expressed in liver lobe; mesonephros; and urinary system. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (transferrin receptor 2).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 36.8 kDa
  Accurate Molecular Mass: 37 kDa
• Protein length: His493-Asn785
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Tfr2 transferrin receptor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Tfr2
• Synonyms: Tfr2; transferrin receptor 2; Trfr2; transferrin receptor protein 2
• Gene ID: 50765
• mRNA Refseq: NM_015799
• Protein Refseq: NP_056614
• UniProt ID: Q9JKX3