TFR2
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Official Full Name
transferrin receptor 2 -
Synonyms
TFR2;transferrin receptor 2;zgc:123043;chromosome: 23;MGC123043;transferrin receptor protein 2;transferrin receptor protein 2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- Mamanlian cells
- HEK293T
- CHO
- His
- Myc&DDK
- His&GST
- Non
- Fc
- Flag
- His&Myc
- mFc
- His&Fc&Avi
Involved Pathway
TFR2 involved in several pathways and played different roles in them. We selected most pathways TFR2 participated on our site, such as Iron metabolism in placenta, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Iron metabolism in placenta | HAMP,IREB2 |
Protein Function
TFR2 has several biochemical functions, for example, co-receptor binding,glycoprotein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFR2 itself. We selected most functions TFR2 had, and list some proteins which have the same functions with TFR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DCDC2,SPSB4,RPLP1,PHF8,PPP4R4,CDK10,HUS1,GOLGA8G,RCOR1,ZNF580 |
| glycoprotein binding | ACE2,FGFR1,RGMA,CNTN1,THBS1,CSNK1D,FBXO2,SDC1,Serpina1b,FBXO6 |
| co-receptor binding | NEO1,HFE,BMP2,DKK1,BMP4 |
| transferrin receptor activity | TFRC,TFR1B,TFR1A |
Interacting Protein
TFR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFR2.
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References
- Wallace, DF; Secondes, ES; et al. A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction. BRITISH JOURNAL OF HAEMATOLOGY 168:891-901(2015).
- Pantopoulos, K; et al. TfR2 links iron metabolism and erythropoiesis. BLOOD 125:1055-1056(2015).
