Recombinant Human TFR2 protein, MYC/DDK-tagged

• Cat.No.: TFR2-16H
• Product Overview: Recombinant Human TFR2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 88.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TFR2 transferrin receptor 2 [ Homo sapiens ]
• Official Symbol: TFR2
• Synonyms: HFE3; TFRC2; transferrin receptor protein 2
• Gene ID: 7036
• mRNA Refseq: NM_003227
• Protein Refseq: NP_003218
• MIM: 604720
• UniProt ID: Q9UP52
• Chromosome Location: 7q22
• Pathway: Iron metabolism in placenta, organism-specific biosystem
• Function: co-receptor binding; glycoprotein binding; transferrin receptor activity