Recombinant Mouse Srf Protein, Myc/DDK-tagged

Cat.No. : Srf-6124M
Product Overview : Purified recombinant protein of mouse full-length serum response factor (Srf), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.
Molecular Mass : 51.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Srf serum response factor [ Mus musculus (house mouse) ]
Official Symbol Srf
Synonyms SRF; serum response factor; AW049942; AW240594
Gene ID 20807
mRNA Refseq NM_020493
Protein Refseq NP_065239
UniProt ID Q9JM73

Not For Human Consumption!

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