Recombinant Mouse Spc24 Protein, Myc/DDK-tagged

• Cat.No.: Spc24-6084M
• Product Overview: Purified recombinant protein of mouse full-length SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) (Spc24), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
• Molecular Mass: 23.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Spc24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) [ Mus musculus (house mouse) ]
• Official Symbol: Spc24
• Synonyms: Spc24; SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae); Spbc; Spbc24; AV109292; 2410030K01Rik; kinetochore protein Spc24; spindle pole body component 24 homolog
• Gene ID: 67629
• mRNA Refseq: NM_026282
• Protein Refseq: NP_080558
• UniProt ID: Q9D083