SPC24
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Official Full Name
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) -
Synonyms
SPBC24
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
SPC24 involved in several pathways and played different roles in them. We selected most pathways SPC24 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPC24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPase Effectors | KTN1,NOXA1,ABI1,KLC3,SGOL2,SKA2,SKA1,RTKN,BAIAP2,RHPN1 |
| PLK1 signaling events | PLK1S1,TPT1,ERCC6L,TPX2,ECT2,NDC80,BORA,TCTN2 |
| Mitotic Metaphase and Anaphase | PDS5B,VRK1,CENPC1,KNTC1,CENPI,CENPL,PDS5A,MIS12,RCC2,CDCA5 |
| Cell cycle | TGFB1A,WAPAL,MDM2,RBBP4,MPEG1.1,RAD17,CUL1B,TRP53,STAG2A,CSNK2A2 |
| Mitotic Prometaphase | CENPP,PDS5A,SMC2,KNTC1,ZWILCH,ERCC6L,NDEL1,ZW10,CENPK,CENPN |
| Cell Cycle, Mitotic | KIF2B,NUP50,CCP110,CDCA5,MASTL,GINS4,MYBL2,TOP2A,GORASP2,CENPO |
| M Phase | NDEL1A,PMF1,NSL1,NCAPH,SGOL2,CLIP1,PANE1,WAPAL,CENPK,VRK1 |
| Mitotic Anaphase | ZWILCH,SKA2,VRK2,SGOL2,PMF1,B9D2,PDS5B,CCDC99,NDEL1,RCC2 |
Protein Function
SPC24 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPC24 itself. We selected most functions SPC24 had, and list some proteins which have the same functions with SPC24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ADCY6,SPI1B,MRPL27,DIXDC1,SLC48A1,BCL9,SH2D2A,CDK11B,ZFP932,TSPYL4 |
Interacting Protein
SPC24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPC24 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPC24.
NDC80;SPC25;ZWINT;MIS12
Resources
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References
- Petrovic, A; Mosalaganti, S; et al. Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization. MOLECULAR CELL 53:591-605(2014).
- Malvezzi, F; Litos, G; et al. A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO JOURNAL 32:409-423(2013).
