Recombinant Mouse Smpdl3b Protein, MYC/DDK-tagged

• Cat.No.: SMPDL3B-15644M
• Product Overview: Purified recombinant protein of Mouse sphingomyelin phosphodiesterase, acid-like 3B (Smpdl3b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro).
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 51.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B [ Mus musculus (house mouse) ]
• Official Symbol: Smpdl3b
• Synonyms: Smpdl3b; sphingomyelin phosphodiesterase, acid-like 3B; Asm; Asml3b; AU045240; 1110054A24Rik; acid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b
• Gene ID: 100340
• mRNA Refseq: NM_133888
• Protein Refseq: NP_598649
• UniProt ID: P58242