Recombinant Mouse Smox Protein, Myc/DDK-tagged

• Cat.No.: Smox-5975M
• Product Overview: Purified recombinant protein of mouse full-length spermine oxidase (Smox), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
• Molecular Mass: 61.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Smox spermine oxidase [ Mus musculus (house mouse) ]
• Official Symbol: Smox
• Synonyms: Smox; spermine oxidase; S; PAO; SMO; PAOh1; B130066H01Rik; spermine oxidase; PAO-1; polyamine oxidase 1; EC 1.5.3.16
• Gene ID: 228608
• mRNA Refseq: NM_145533
• Protein Refseq: NP_663508
• UniProt ID: Q99K82