Recombinant Mouse Smc6 Protein, Myc/DDK-tagged

• Cat.No.: Smc6-5964M
• Product Overview: Purified recombinant protein of mouse full-length structural maintenance of chromosomes 6 (Smc6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 127.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Smc6 structural maintenance of chromosomes 6 [ Mus musculus (house mouse) ]
• Official Symbol: Smc6
• Synonyms: SMC6; structural maintenance of chromosomes 6; structural maintenance of chromosomes protein 6; mSMC6; SMC protein 6; SMC6 structural maintenance of chromosomes 6-like 1; SMC-6; Smc6l1; AA990493; AU018782; AW742439; mKIAA4103; 2810489L22Rik; 3830418C19Rik; KIAA4103; MGC96146
• Gene ID: 67241
• mRNA Refseq: NM_025695
• Protein Refseq: NP_079971
• UniProt ID: Q924W5