SMC6
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Official Full Name
structural maintenance of chromosomes 6 -
Overview
Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene. -
Synonyms
SMC6;structural maintenance of chromosomes 6;SMC6 structural maintenance of chromosomes 6 like 1 (yeast) , SMC6L1;structural maintenance of chromosomes protein 6;FLJ22116;SMC protein 6;SMC6 structural maintenance of chromosomes 6-like 1;SMC-6;hSMC
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SMC6-2812H | Recombinant Human SMC6, GST-tagged | E.coli | Human | GST | 740-1091aa | |
| SMC6-15614M | Recombinant Mouse SMC6 Protein | Mammalian Cell | Mouse | His |
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| SMC6-1665HCL | Recombinant Human SMC6 293 Cell Lysate | HEK293 | Human | Non |
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| SMC6-5904H | Recombinant Human SMC6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Smc6-5964M | Recombinant Mouse Smc6 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SMC6-8472M | Recombinant Mouse SMC6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SMC6-8472M-B | Recombinant Mouse SMC6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SMC6 involved in several pathways and played different roles in them. We selected most pathways SMC6 participated on our site, such as Metabolism of proteins,Post-translational protein modification,SUMO E3 ligases SUMOylate target proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-translational protein modification | SUMF2,SEC16B,DPH3,SENP5,ARSI,YKT6,DHPS,CNIH3,SCFD1,ADAMTS18 |
| SUMOylation of DNA damage response and repair proteins | SCMH1,PHC3,SMC5,PHC1,NSMCE1,NSMCE4A,CBX8,EID3,RNF2,NSMCE2 |
| SUMOylation | PHC3,CBX8,SENP1,RING1,PHC2,SAE1,NSMCE4A,NSMCE1,RNF2,SMC5 |
| SUMO E3 ligases SUMOylate target proteins | NSMCE2,SMC5,CBX8,PHC3,NSMCE1,EID3,NSMCE4A,RING1,RNF2,CBX4 |
| Metabolism of proteins | DDX11,GCNT3,DPAGT1,ARL2,C8orf84,APCS,SLC38A8,PPP6R1,FXC1,ADAMTSL1 |
Protein Function
SMC6 has several biochemical functions, for example, ATP binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC6 itself. We selected most functions SMC6 had, and list some proteins which have the same functions with SMC6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | RAD51L3,ARAF,PCCA,ROS1,CDC34A,ORC4,GUK1,GALK1,CDKL4,JAK3 |
| protein binding | TADA3,ATG7,PODXL2,MMP14,CD69,SPG7,CDK10,PPP2R5B,SPRY4,RBM3 |
| ubiquitin protein ligase binding | CD40,EGR2,VCP,CDC34B,FANCL,CUL1,SKI,HIF1A,BLZF1,RELA |
Interacting Protein
SMC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC6.
NSMCE1;SMC5;NDNL2;NSMCE2
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