Recombinant Mouse Slc25a33 Protein, Myc/DDK-tagged

• Cat.No.: Slc25a33-5914M
• Product Overview: Purified recombinant protein of mouse full-length solute carrier family 25, member 33 (Slc25a33), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration. Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production. Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 35 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slc25a33 solute carrier family 25, member 33 [ Mus musculus (house mouse) ]
• Official Symbol: Slc25a33
• Synonyms: Slc25a33; solute carrier family 25, member 33; Pn; Pnc1; 5730438N18Rik; solute carrier family 25 member 33; mitochondrial carrier protein; novel mitochondrial carrier protein domains containing protein
• Gene ID: 70556
• mRNA Refseq: NM_027460
• Protein Refseq: NP_081736
• UniProt ID: Q3TZX3