Recombinant Mouse Six5 Protein, Myc/DDK-tagged

• Cat.No.: Six5-5890M
• Product Overview: Purified recombinant protein of mouse full-length sine oculis-related homeobox 5 (Six5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3.
• Molecular Mass: 73.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Six5 sine oculis-related homeobox 5 [ Mus musculus (house mouse) ]
• Official Symbol: Six5
• Synonyms: SIX5; sine oculis-related homeobox 5 homolog (Drosophila); homeobox protein SIX5; sine oculis homeobox homolog 5; DM locus-associated homeodomain protein homolog; Dmahp; MDMAHP; TrexBF
• Gene ID: 20475
• mRNA Refseq: NM_011383
• Protein Refseq: NP_035513
• UniProt ID: P70178