Recombinant Mouse Sh3pxd2b Protein, Myc/DDK-tagged

• Cat.No.: Sh3pxd2b-5850M
• Product Overview: Purified recombinant protein of mouse full-length SH3 and PX domains 2B (Sh3pxd2b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 101.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sh3pxd2b SH3 and PX domains 2B [ Mus musculus (house mouse) ]
• Official Symbol: Sh3pxd2b
• Synonyms: Sh3pxd2b; SH3 and PX domains 2B; Tks; Fad4; TSK4; Tks4; fad49; G431001E03Rik; SH3 and PX domain-containing protein 2B; factor for adipocyte differentiation 49; tyrosine kinase substrate with four SH3 domains
• Gene ID: 268396
• mRNA Refseq: NM_177364
• Protein Refseq: NP_796338
• UniProt ID: A2AAY5