Recombinant Human SH3PXD2B Protein, MYC/DDK-tagged

• Cat.No.: SH3PXD2B-1331H
• Product Overview: Recombinant human SH3PXD2B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 101.4 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SH3 and PX domains 2B [ Homo sapiens ]
• Official Symbol: SH3PXD2B
• Synonyms: FAD49; FTHS; HOFI; KIAA1295; TKS4; TSK4
• Gene ID: 285590
• mRNA Refseq: NM_001017995.2
• Protein Refseq: NP_001017995.1
• MIM: 613293
• UniProt ID: A1X283