Recombinant Mouse Sgk1 Protein, Myc/DDK-tagged

• Cat.No.: Sgk1-5824M
• Product Overview: Purified recombinant protein of mouse full-length serum/glucocorticoid regulated kinase 1 (Sgk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 48.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sgk1 serum/glucocorticoid regulated kinase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Sgk1
• Synonyms: Sgk1; serum/glucocorticoid regulated kinase 1; Sg; Sgk; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; EC 2.7.11.1
• Gene ID: 20393
• mRNA Refseq: NM_011361
• Protein Refseq: NP_035491
• UniProt ID: Q9WVC6