Recombinant Mouse Rufy3 Protein, Myc/DDK-tagged

• Cat.No.: Rufy3-5648M
• Product Overview: Purified recombinant protein of mouse full-length RUN and FYVE domain containing 3 (Rufy3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in the generation of neuronal polarity formation and axon growth. Implicated in the formation of a single axon by developing neurons. May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes. Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery. Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones. Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner.
• Molecular Mass: 53.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rufy3 RUN and FYVE domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Rufy3
• Synonyms: RUFY3; RUN and FYVE domain containing 3; protein RUFY3; singar; rap2 interacting protein x; rap2-interacting protein x; single axon-regulated protein; Ripx; Rpipx; AW455998; AW538594; mKIAA0871; D5Bwg0860e; 2810428M05Rik; 6330416M07Rik
• Gene ID: 52822
• mRNA Refseq: NM_027530
• Protein Refseq: NP_081806
• UniProt ID: Q9D394