Recombinant Mouse Rock2 Protein, His-tagged

• Cat.No.: Rock2-2025M
• Product Overview: Recombinant Mouse Rock2 Protein (Leu904-Gly1140) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Leu904-Gly1140
• Description: Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; protein phosphorylation; and regulation of signal transduction. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway via death domain receptors; nervous system development; and positive regulation of centrosome duplication. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and spindle pole centrosome. Is expressed in several structures, including central nervous system; genitourinary system; heart; musculature; and somite. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.0 kDa
  Accurate Molecular Mass: 31 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Rock2 Rho-associated coiled-coil containing protein kinase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Rock2
• Synonyms: ROCK2; Rho-associated coiled-coil containing protein kinase 2; rho-associated protein kinase 2; p164 ROCK-2; Rho-associated coiled-coil forming kinage 2; rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; Rock2m; Rock-II; ROKalpha; mKIAA0619; Rho-kinase; B230113H15Rik
• Gene ID: 19878
• mRNA Refseq: NM_009072
• Protein Refseq: NP_033098
• UniProt ID: P70336