Recombinant Mouse Rnf220 Protein, Myc/DDK-tagged

• Cat.No.: Rnf220-5555M
• Product Overview: Purified recombinant protein of mouse full-length ring finger protein 220 (Rnf220), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 and promotes Wnt signaling.
• Molecular Mass: 63.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rnf220 ring finger protein 220 [ Mus musculus (house mouse) ]
• Official Symbol: Rnf220
• Synonyms: RNF220; ring finger protein 220; E3 ubiquitin-protein ligase Rnf220; AV302541; 4732477A13; 4931406I20Rik; 5730503K05Rik
• Gene ID: 66743
• mRNA Refseq: NM_025739
• Protein Refseq: NP_080015
• UniProt ID: Q6PDX6