Recombinant Mouse Rbfox2 Protein, Myc/DDK-tagged

• Cat.No.: Rbfox2-5407M
• Product Overview: Purified recombinant protein of mouse full-length RNA binding protein, fox-1 homolog (C. elegans) 2 (Rbfox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. Seems to act as a coregulatory factor of ER-alpha.
• Molecular Mass: 41 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 [ Mus musculus (house mouse) ]
• Official Symbol: Rbfox2
• Synonyms: RBFOX2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA binding protein fox-1 homolog 2; fox-1 homolog B; fox-1 homolog Fxh; RNA-binding protein 9; Fyn-binding molecule 2; RNA binding motif protein 9; RNA-binding motif protein 9; hexaribonucleotide binding protein 2; hexaribonucleotide-binding protein 2; Fxh; Fbm2; Rbm9; Hrnbp2; AA407676; AI118529; 2810460A15Rik
• Gene ID: 93686
• mRNA Refseq: NM_001110828
• Protein Refseq: NP_001104298
• UniProt ID: Q8BP71