Recombinant Mouse Rap1b Protein, Myc/DDK-tagged

• Cat.No.: Rap1b-5372M
• Product Overview: Purified recombinant protein of mouse full-length RAS related protein 1b (Rap1b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
• Molecular Mass: 21.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rap1b RAS related protein 1b [ Mus musculus (house mouse) ]
• Official Symbol: Rap1b
• Synonyms: RAP1B; RAS related protein 1b; ras-related protein Rap-1b; GTP-binding protein smg p21B; 2810443E11Rik
• Gene ID: 215449
• mRNA Refseq: NM_024457
• Protein Refseq: NP_077777
• UniProt ID: Q99JI6