Recombinant Mouse Rab3gap1 Protein, Myc/DDK-tagged

• Cat.No.: Rab3gap1-5319M
• Product Overview: Purified recombinant protein of mouse full-length RAB3 GTPase activating protein subunit 1 (Rab3gap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
• Molecular Mass: 110.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab3gap1 RAB3 GTPase activating protein subunit 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rab3gap1
• Synonyms: RAB3GAP1; RAB3 GTPase activating protein subunit 1; rab3 GTPase-activating protein catalytic subunit; rab3-GAP p130; RAB3 GTPase-activating protein 130 kDa subunit; p130; Rab3gap; AL117896; 1700003B17Rik; 4732493F09Rik
• Gene ID: 226407
• mRNA Refseq: NM_178690
• Protein Refseq: NP_848805
• UniProt ID: Q80UJ7