RAB3GAP1
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Official Full Name
RAB3 GTPase activating protein subunit 1 (catalytic) -
Overview
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants. -
Synonyms
RAB3GAP1;RAB3 GTPase activating protein subunit 1 (catalytic);rab3 GTPase-activating protein catalytic subunit;KIAA0066;RAB3GAP;RAB3GAP130;WARBM1;rab3-GAP p130;RAB3 GTPase-activating protein 130 kDa subunit;P130;DKFZp434A012
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- His&Fc&Avi
- Flag
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAB3GAP1-2122H | Recombinant Human RAB3GAP1, GST-tagged | E.coli | Human | GST | 502-851aa | |
| RAB3GAP1-13823M | Recombinant Mouse RAB3GAP1 Protein | Mammalian Cells | Mouse | His |
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| RAB3GAP1-4864Z | Recombinant Zebrafish RAB3GAP1 | Mammalian Cells | Zebrafish | His |
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| RAB3GAP1-1837H | Recombinant Human RAB3GAP1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| RAB3GAP1-1837H-B | Recombinant Human RAB3GAP1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RAB3GAP1-1954HFL | Recombinant Full Length Human RAB3GAP1 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| RAB3GAP1-304H | Recombinant Human RAB3GAP1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Rab3gap1-5319M | Recombinant Mouse Rab3gap1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| RAB3GAP1-7356M | Recombinant Mouse RAB3GAP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RAB3GAP1-7356M-B | Recombinant Mouse RAB3GAP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RAB3GAP1 involved in several pathways and played different roles in them. We selected most pathways RAB3GAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB3GAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RAB3GAP1 has several biochemical functions, for example, GTPase activator activity,Rab GTPase binding,contributes_to Rab guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB3GAP1 itself. We selected most functions RAB3GAP1 had, and list some proteins which have the same functions with RAB3GAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | ARHGAP19,ARHGAP32,RGS5A,RGS12B,TBC1D8,CHN2,ARHGAP1,ARHGAP35,RGS4,PLEKHG6 |
| Rab GTPase binding | RPH3AL,RIN3,TBC1D30,MYO5B,RILP,RAB11FIP1,NGFR,UNC13D,RAB11FIP4B,TBC1D7 |
| contributes_to Rab guanyl-nucleotide exchange factor activity | RAB3GAP2 |
Interacting Protein
RAB3GAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB3GAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB3GAP1.
MAP1LC3A;PTP4A3;RXRB;MAGEA6;GSTK1;pi3p
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