Recombinant Mouse Rab1b Protein, Myc/DDK-tagged

• Cat.No.: Rab1b-5295M
• Product Overview: Purified recombinant protein of mouse full-length RAB1B, member RAS oncogene family (Rab1b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment.
• Molecular Mass: 22.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab1b RAB1B, member RAS oncogene family [ Mus musculus (house mouse) ]
• Official Symbol: Rab1b
• Synonyms: RAB1B; RAB1B, member RAS oncogene family; ras-related protein Rab-1B; 1110011F09Rik
• Gene ID: 76308
• mRNA Refseq: NM_029576
• Protein Refseq: NP_083852
• UniProt ID: Q9D1G1