RAB1B
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Official Full Name
RAB1B, member RAS oncogene family -
Overview
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic;surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for;vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 (PubMed 9030196); Alvarez et;al., 2003 (PubMed 12802079)). -
Synonyms
RAB1B;RAB1B, member RAS oncogene family;ras-related protein Rab-1B;small GTP-binding protein
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- His&GST
- Fc
- Non
- His&Strep
- GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
RAB1B involved in several pathways and played different roles in them. We selected most pathways RAB1B participated on our site, such as Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Legionellosis | SAR1B,IL12A,CYCS,CASP7,HSPA1B,RAB1A,HSPA1L,EEF1G,VCP,EEF1A1 |
Protein Function
RAB1B has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB1B itself. We selected most functions RAB1B had, and list some proteins which have the same functions with RAB1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB6C,LRRK2,RRAS2,GBP5,DNM1,TUBA4L,EIF2S3Y,RAB31,TUBA1A,GNA14 |
| GTP binding | TUBB6,TUBA1L,RAB43,SRPRB,SEPT7,EEF2,RAB7B,MXB,RIT1,EIF2S3Y |
| protein binding | PATL1,BORA,SGCG,PEX19,MXD1,FAM162A,HACE1,CACNA1SB,TSPAN1,ING1 |
Interacting Protein
RAB1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB1B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB1B.
RUSC2;OCRL;lepB;3',5'-cyclic amp;7-ch-c_amp;mant-gdp;MCC;HLA-B;VHL;GOLGA2;q81lj8_bacan;SMARCC2;MICAL1;TOMM40L;pi3p
Resources
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References
- Hutt, DM; Balch, WE; et al. Rab1b silencing using small interfering RNA for analysis of disease-specific function. SMALL GTPASES IN DISEASE, PART A 438:1-10(2008).
- Mochizuki, Y; Ohashi, R; et al. Phosphatidylinositol 3-Phosphatase Myotubularin-related Protein 6 (MTMR6) Is Regulated by Small GTPase Rab1B in the Early Secretory and Autophagic Pathways. JOURNAL OF BIOLOGICAL CHEMISTRY 288:1009-1021(2013).
