Recombinant Mouse Psme3 Protein, Myc/DDK-tagged
Cat.No. : | Psme3-5203M |
Product Overview : | Purified recombinant protein of mouse full-length proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) (Psme3), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition. |
Molecular Mass : | 29.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) [ Mus musculus (house mouse) ] |
Official Symbol | Psme3 |
Synonyms | PSME3; proteaseome (prosome, macropain) 28 subunit, 3; proteasome activator complex subunit 3; REG-gamma; ki nuclear autoantigen; 11S regulator complex subunit gamma; proteasome activator 28 subunit gamma; activator of multicatalytic protease subunit 3; Ki; pa28g; AA410043; AU020960; REGgamma; PA28gamma |
Gene ID | 19192 |
mRNA Refseq | NM_011192 |
Protein Refseq | NP_035322 |
UniProt ID | P61290 |
◆ Recombinant Proteins | ||
PSME3-13603M | Recombinant Mouse PSME3 Protein | +Inquiry |
Psme3-5203M | Recombinant Mouse Psme3 Protein, Myc/DDK-tagged | +Inquiry |
PSME3-570C | Recombinant Cynomolgus Monkey PSME3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSME3-7228M | Recombinant Mouse PSME3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSME3-1923C | Recombinant Chicken PSME3 | +Inquiry |
◆ Cell & Tissue Lysates | ||
PSME3-2740HCL | Recombinant Human PSME3 293 Cell Lysate | +Inquiry |
PSME3-2739HCL | Recombinant Human PSME3 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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