Recombinant Mouse Ppp1r11 Protein, Myc/DDK-tagged

• Cat.No.: Ppp1r11-5057M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 1, regulatory inhibitor subunit 11 (Ppp1r11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1.
• Molecular Mass: 14.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp1r11 protein phosphatase 1, regulatory inhibitor subunit 11 [ Mus musculus (house mouse) ]
• Official Symbol: Ppp1r11
• Synonyms: Ppp1r11; protein phosphatase 1, regulatory inhibitor subunit 11; HCG; HCG-; Hcgv; Tcte5; Tctex5; Tctex-5; AV117883; 1500041B02Rik; E3 ubiquitin-protein ligase PPP1R11; T-complex testis expressed protein 5; protein phosphatase 1 regulatory subunit 11; t-complex testis-expressed 5; EC 2.3.2.27
• Gene ID: 76497
• mRNA Refseq: NM_029632
• Protein Refseq: NP_083908
• UniProt ID: Q8K1L5