Recombinant Mouse Poli Protein, Myc/DDK-tagged
Cat.No. : | Poli-4990M |
Product Overview : | Purified recombinant protein of mouse full-length polymerase (DNA directed), iota (Poli), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity. |
Molecular Mass : | 75.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Poli polymerase (DNA directed), iota [ Mus musculus (house mouse) ] |
Official Symbol | Poli |
Synonyms | POLI; polymerase (DNA directed), iota; DNA polymerase iota; RAD30 homolog B; Rad30b |
Gene ID | 26447 |
mRNA Refseq | NM_001136090 |
Protein Refseq | NP_001129562 |
UniProt ID | Q6R3M4 |
◆ Recombinant Proteins | ||
POLI-1020H | Recombinant Human POLI Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
POLI-1834H | Recombinant Human POLI, His-tagged | +Inquiry |
POLI-1835H | Recombinant Human POLI protein, GST-tagged | +Inquiry |
Poli-4990M | Recombinant Mouse Poli Protein, Myc/DDK-tagged | +Inquiry |
POLI-1526H | Recombinant Human POLI protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
POLI-3046HCL | Recombinant Human POLI 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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