POLI
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Official Full Name
polymerase (DNA directed) iota -
Synonyms
POLI;polymerase (DNA directed) iota;RAD3OB, RAD30B;DNA polymerase iota;Eta 2;ETA2;RAD 30B;RAD30 homolog B;RAD30B;RAD3OB;polymerase (DNA-directed), iota
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- DDK
- Myc
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLI-1834H | Recombinant Human POLI, His-tagged | E.coli | Human | His | 1-340aa | |
| POLI-13081M | Recombinant Mouse POLI Protein | Mammalian Cells | Mouse | His |
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| POLI-1526H | Recombinant Human POLI protein | E.coli | Human | Non |
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| POLI-2561Z | Recombinant Zebrafish POLI | Mammalian Cells | Zebrafish | His |
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| POLI-3046HCL | Recombinant Human POLI 293 Cell Lysate | HEK293 | Human | Non |
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| POLI-1020H | Recombinant Human POLI Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| POLI-1835H | Recombinant Human POLI protein, GST-tagged | E.coli | Human | GST | 1-340 a.a. |
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| Poli-4990M | Recombinant Mouse Poli Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| POLI-6911M | Recombinant Mouse POLI Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| POLI-6911M-B | Recombinant Mouse POLI Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
POLI involved in several pathways and played different roles in them. We selected most pathways POLI participated on our site, such as DNA Damage Bypass,DNA Repair,Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | APITD1,STRA13,REV3L,HER9,ERCC1,CDK5R2,C19orf40,FAN1,BRIP1,FUZ |
| DNA Damage Bypass | POLD3,RAD18,SPRTN,USP10,MAD2L2,DDB1,ZBTB32,UBE2L6,USP43,DTL |
| Translesion synthesis by POLI | MAD2L2 |
| DNA Repair | UBE2V2,NFRKB,MCRS1,RNF111,EYA4,KIAA0146,THRSP,TIPIN,COPS6,SPRTN |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | USP10,SPRTN,USP43A,USP43,KIAA0101 |
| Termination of translesion DNA synthesis | USP43,USP10,USP43A,KIAA0101 |
Protein Function
POLI has several biochemical functions, for example, DNA-directed DNA polymerase activity,damaged DNA binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLI itself. We selected most functions POLI had, and list some proteins which have the same functions with POLI. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EXOC7,AKAP12,CCDC137,DDX39A,CDC40,FAM9A,CERS2,EIF2AK3,PTMA,NR5A2 |
| damaged DNA binding | H2AFX,RPS3,ERCC1,OGG1,HMGB2,RAD18,TP53,DCLRE1A,NEIL1,TRP53 |
| metal ion binding | ZBTB16A,ZNF557,RXFP1,PRG4B,ZNF254,ARSD,ARSJ,NUBPL,SALL4,GM757 |
| DNA-directed DNA polymerase activity | POLB,POLD3,DNTT,PRIMPOL,POLA1,POLG2,POLH,POLG,PAPD7,POLE |
Interacting Protein
POLI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLI here. Most of them are supplied by our site. Hope this information will be useful for your research of POLI.
TRIM39;DAZAP2;ZBTB44;TMEM239;TRAF6;UBC
Resources
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References
- Malafronte, J; et al. OPERA AND ORATORIO MOZART: Don Giovanni Opus Arte 1145D (Bystrom, Gens, Watts; Kwiecien, Poli, Esposito, Kimberg, Tsymbalyuk; Orchestra of the Royal Opera House, Luisotti). OPERA NEWS 79:57-57(2015).
- Gallagher, MC; Davenport, J; et al. The invasive barnacle species, Austrominius modestus: Its status and competition with indigenous barnacles on the Isle of Cumbrae, Scotland. ESTUARINE COASTAL AND SHELF SCIENCE 152:134-141(2015).
