Recombinant Mouse Papss2 Protein, Myc/DDK-tagged

• Cat.No.: Papss2-4675M
• Product Overview: Purified recombinant protein of mouse full-length 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth.
• Molecular Mass: 70.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Papss2
• Synonyms: PAPSS2; 3-phosphoadenosine 5-phosphosulfate synthase 2; bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2; SK 2; PAPSS 2; brachymorphic; PAPS synthase 2; sulfurylase kinase 2; bm; Sk2; AtpsU2; Atpsk2; AI159688; 1810018P12Rik
• Gene ID: 23972
• mRNA Refseq: NM_011864
• Protein Refseq: NP_035994
• UniProt ID: O88428