Recombinant Mouse Nr2e3 Protein, Myc/DDK-tagged

• Cat.No.: Nr2e3-4490M
• Product Overview: Purified recombinant protein of mouse full-length nuclear receptor subfamily 2, group E, member 3 (Nr2e3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression.
• Molecular Mass: 43.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nr2e3 nuclear receptor subfamily 2, group E, member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Nr2e3
• Synonyms: NR2E3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; retinal degeneration 7; retina-specific nuclear receptor; PNR; RNR; rd7; A930035N01Rik
• Gene ID: 23958
• mRNA Refseq: NM_013708
• Protein Refseq: NP_038736
• UniProt ID: Q9QXZ7