Recombinant Human NR2E3 protein, His & GST-tagged

• Cat.No.: NR2E3-1090H
• Product Overview: Recombinant Human NR2E3 aa. (Met1~Asn410 fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&GST
• ProteinLength: Met1~Asn410
• Description: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Form: Freeze-dried powder
• Molecular Mass: 75kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >92%
• Characteristic: The isoelectric point is 8.2.
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex.

Gene Information

• Gene Name: NR2E3 nuclear receptor subfamily 2 group E member 3 [ Homo sapiens (human) ]
• Official Symbol: NR2E3
• Synonyms: NR2E3; nuclear receptor subfamily 2 group E member 3; PNR; RNR; rd7; ESCS; RP37; photoreceptor-specific nuclear receptor; retina-specific nuclear receptor
• Gene ID: 10002
• mRNA Refseq: NM_014249.3
• Protein Refseq: NP_055064.1
• UniProt ID: Q9Y5X4